Diabetes Articles
  • Sign Up
FacebookTwitterDiggStumbleuponGoogle BookmarksRedditLinkedinPinterest

Glaxo, Tolerx diabetes drug fails in study

NEW YORK - Tolerx Inc. and GlaxoSmithKline PLC said Friday their potential diabetes drug failed to meet its goal in a late-stage study.

The companies are studying otelixizumab as a potential treatment for patients with Type 1 diabetes. In Type 1 diabetes, the autoimmune system destroys insulin producing cells, making it necessary for patients to receive insulin boosts. The condition is fatal if not treated with insulin.

Type 2 diabetes is more common and involves the body not being able to properly use the insulin it produces.

The companies have suspended a similar late-stage study on the drug, pending review of the failed study.

"While we are disappointed in the DEFEND-1 (study) results of otelixizumab, we remain committed to the development and commercialization of the candidates in our pipeline, each of which has a distinct mechanism and target for correcting abnormal immune responses," said Douglas J. Ringler, president and CEO of Tolerx, in a statement.

Tolerx is a privatel held biotechnology company based in Cambridge, Mass.

Sources include

Read Full Article

Find out if you qualify for discount Diabetic testing supplies, free offers or other running discounts at this time.

  1. First Name*
    Enter first name
  2. Last Name*
    Enter last name
  3. Phone*
    Enter valid US phone number
  4. E-mail*
    Enter email address

By submitting this form I authorize to be contacted by telephone. Please be assured that we value and protect your privacy. Co-Pays and Deductibles may apply.

About The Diabetes Network

The Diabetes Network was developed with the idea that people living with diabetes needed a central place to go for resources as well as get ideas, suggestions and encouragement. We have put a lot of effort into this website to make it easy and fun to navigate as well as informative so that you can have a voice when it comes to managing your diabetes. Please let us know how we can improve this website to better suit your needs.

More about our Mission

We're on a mission to make the healthcare community more technologically advanced than ever before. This website adapts to fit your tablet, iPad®, iPhone®, Android® or other smartphone. Just one of the ways we are working to make life easier for those living with Diabetes. Learn More...